Pharmacoevidence Quote Builder

Your name / initials

Project name

Client / company

Therapeutic area

Project start date

Currency

Fill in details

Step 1 — Citation volume

Ti/Ab citations to screen

Billed on this count only — full-text (~10%) and extraction (~10% of FT) included in rate

Number of SLRs in programme

Ti/Ab screening

1,000

entered

✓ Billed here

Full-text (est.)

100

~10% Ti/Ab

Incl. in rate

Extractions (est.)

~10% FT

Incl. in rate

Step 2 — Delivery model

Human-only

Traditional SLR

$11/citation

Dual human screening. Full audit trail. Gold standard for HTA.

AI-assisted

AI + Human review

$6/citation

AI pre-screening with human verification at each stage.

Predominantly AI

AI + Human-in-loop

$3/citation

AI screens; human reviews at key checkpoints only.

Step 3 — Contract type

Single programme

0% off

Standard rates

2-year retainer

2% off

All programme costs

3-year retainer

4% off

Priority SLA & dedicated team

Step 4 — Deliverables

Protocol

SLR report

ES slide deck

Feasibility

ITC / NMA

MAIC

Abstract/poster

Manuscript

Number of MAIC comparators

AI-assisted deliverable discount (applies 50% rate by default — adjust in Rate setup)

AI: Protocol

AI: Report

AI: Deck

AI: Feasibility

AI: ITC/NMA

AI: MAIC

Toggle to apply AI-assisted rate for individual deliverables (default: conventional rate)

Cost breakdown

Human-only

Configure above

Screening

—

Documents

—

Analytics

—

Publications

—

Dossiers

—

Our total (after discount)

—

Typical CRO estimate

—

Estimated saving

—

SLR Update & QC — Quote for a literature update search on an existing SLR (with report options) and/or an independent quality check of screening decisions and data extractions.

A — Update search

New Ti/Ab hits from update search

New records found since original search date

Delivery model for update

Update Ti/Ab hits

500

✓ Billed here

Full-text (est.)

~10%

Extractions (est.)

~10% FT

Delivery model

AI-assisted

Rate applied

$6/citation

Screening cost

$3,000

B — Report deliverable

No report

Screening only

Update existing report

Amend & re-issue original

New standalone report

Full report from scratch

Original report base cost

Update scope (% of original)

Update cost:$6,00060% of $10,000

C — QC of original SLR

Screening QC

Citations to re-screen

Typically 10–20% of original Ti/Ab

QC cost per citation

Lower than screening — verification only

Extraction QC

Extractions to re-check

QC cost per extraction

Include QC findings memo

QC report cost

Screening QC

—

Extraction QC

—

Total QC—

Update & QC — cost summary

AI-assisted update

Configure sections above

Update screening

—

Report deliverable

—

QC total

—

QC memo

—

Grand total

—

Screening portion

—

Report & QC portion

—

Search update frequency

Select how often new literature is searched. Deliverables can update at a lower frequency than the search itself.

Off

Standard only

Annual

1×/year

Half-yearly

2×/year

Quarterly

4×/year

Monthly

12×/year

New citations per update (% of original Ti/Ab)

20% = ~200 new citations if original was 1,000

Programme duration (years)

Regulatory & HTA dossier deliverables

Select dossiers required. Choose AI-assisted or conventional approach and optionally add a Targeted Literature Review (TLR) per disease area. Costs pull from Rate setup tab.

Dossier cost summary

Selected dossiers

One-time dossier cost

—

Annual update cost

—

JCA support — EU HTAR package

Joint Clinical Assessment requires rapid evidence submission within EMA timelines. Configure your JCA package below.

Rapid SLR updates (PICO-aligned)

Targeted searches scoped to JCA PICO(S). Typically 2–4 focused SLRs. Accelerated 4–6 week turnaround.

Number of JCA SLRs

Ti/Ab citations per SLR

SLR cost: —

PICO simulation & scenario analysis

Alternative PICO definitions to anticipate Member State variations. Each includes evidence mapping and gap analysis.

Number of PICO simulations

Cost per PICO simulation

PICO cost: —

ITC / NMA (JCA-formatted)

NMA or MAIC structured to JCA requirements including statistical analysis plan and HTAR-formatted results.

ITC / NMA

MAIC comparators (if applicable)

ITC cost: —

JCA dossier development

HTAR template sections B4–B7, evidence tables, SLR methodology appendix. Includes QC and review rounds.

Dossier complexity

Member State adaptations

Dossier cost: —

Clinical expert input & RTQ support

Structured clinical expert questionnaire, evidence gap narrative, and response-to-questions support.

Expert input

RTQ rounds anticipated

Expert input cost: —

JCA package total

SLRs & screening

—

PICO simulations

—

ITC / NMA

—

Dossier development

—

Expert input

—

Total JCA package

—

Model type

Select the economic modelling deliverable(s) required. Choose development of a new model or update of an existing one, and select model type. Costs are configurable in Rate setup.

Model specifications

Disease area / therapeutic indication

Number of health states / comparators

Primary HTA body target

Sensitivity analysis (PSA required?)

Model validation required?

Report & technical appendix

Model development cost

Base model cost

—

Complexity uplift

—

Validation

—

Documentation

—

Total model cost

—

Delivery mode

New development

Selected models

None

Screening rates (per Ti/Ab citation)

Human-onlyTraditional SLR$/cit.

AI-assistedAI + Human review$/cit.

Predominantly AIAI + Human-in-loop$/cit.

Fixed deliverable costs

Protocol

ConventionalProtocol — base$

AI-assistedProtocol — AI-assisted$

Protocol uplift / additional SLR$

SLR report

ConventionalSLR report — base$

AI-assistedSLR report — AI-assisted$

Report uplift / additional SLR$

Adjustable per project complexity

ES slide deck

ConventionalES deck — base$

AI-assistedES deck — AI-assisted$

Deck uplift / additional SLR$

Feasibility & Analytics

ConventionalFeasibility study$

AI-assistedFeasibility — AI-assisted$

ConventionalITC / NMA$

AI-assistedITC / NMA — AI-assisted$

ConventionalMAIC (per comparator)$

AI-assistedMAIC — AI-assisted$

Publications

Abstract / poster$

Manuscript$

Contract discounts

2-year retainer discount (%)%

3-year retainer discount (%)%

Dossier rates

AI-assisted dossiers default to $50,000; conventional $120,000–$140,000. TLR add-on is optional — users can toggle it per dossier in the Dossiers tab.

Model development rates

Full rate card

Reflects current Rate setup values.

Deliverable	Human/Conventional	AI-assisted	Notes
SLR screening Per Ti/Ab citation; FT & extraction incl.	$11/cit	$6/cit	Also: Pred. AI $3/cit
Protocol	$4,000	$2,000	+$1,000 per additional SLR
SLR report	$10,000	$5,000	+$3,000 per additional SLR (adjustable)
ES slide deck	$5,000	$2,500	+$3,000 per additional SLR
Feasibility study	$20,000	$10,000	Flat rate
ITC / NMA	$20,000	$10,000	Full NMA included
MAIC	$15,000	$7,500	Per comparator
Abstract / poster	$8,000		Per output
Manuscript	$16,000		Per manuscript
2-year retainer	2% off		All costs
3-year retainer	4% off		Priority SLA + dedicated team

Project timeline & Gantt chart

Timelines are auto-populated from your deliverable selections and project start date. Adjust duration (days) per activity below. The Gantt chart updates live.

No deliverables selected yet — configure in the New SLR quote tab first, then return here.